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LabTestsOnDemand

9-test private STI panel

Comprehensive Sexual Health Panel

The broadest private STI panel LabTestsOnDemand offers — nine tests including HSV-1, HSV-2, and Trichomoniasis, drawn in person at Labcorp, with one flat self-pay price.

Order the Comprehensive Panel — $269

$269 flat self-pay · 9 STI tests · Labcorp collection · No insurance billing by LabTestsOnDemand

What is the Comprehensive Sexual Health Panel?

The Comprehensive Sexual Health Panel is a nine-test private self-pay STI screen. It covers the six infections in the Standard Panel — HIV, Syphilis, Hepatitis B, Hepatitis C, Gonorrhea, and Chlamydia — and adds three that many narrower panels leave out: HSV-1, HSV-2, and Trichomoniasis.

This is the panel to choose when you want the broadest coverage LabTestsOnDemand offers in a single order. Every sample is collected in person by trained Labcorp staff at a Labcorp Patient Service Center — it is not an at-home kit.

The nine tests included

  • ✓HIV
  • ✓Syphilis
  • ✓Hepatitis B
  • ✓Hepatitis C
  • ✓Gonorrhea
  • ✓Chlamydia
  • ✓HSV-1 (herpes)
  • ✓HSV-2 (herpes)
  • ✓Trichomoniasis

Neither this panel nor any single STI panel covers every possible sexually transmitted infection. HPV, for example, is not included — see the FAQ below for details.

Why HSV-1, HSV-2, and Trichomoniasis are included

Why HSV-1 testing matters

HSV-1 is extremely common — the CDC estimates roughly half of U.S. adults have HSV-1, and although it is best known as the cause of oral cold sores, it is now a leading cause of new genital herpes cases as well (per CDC). Most people with HSV-1 have never had it confirmed with a lab test. A type-specific IgG antibody test can identify past HSV-1 infection even without visible sores, which matters for informed conversations with partners and for interpreting future outbreaks.

Why HSV-2 testing matters

HSV-2 is the classic cause of genital herpes and, per the CDC, most people who have HSV-2 do not know it — outbreaks can be mild, atypical, or absent for long stretches. Type-specific HSV-2 IgG testing is the standard serologic method the CDC recommends when herpes blood testing is used, and it distinguishes HSV-2 from HSV-1 (a distinction that meaningfully changes counseling and transmission expectations).

Why Trichomoniasis is included

Trichomoniasis (caused by the parasite Trichomonas vaginalis) is one of the most common curable STIs in the U.S., yet it is frequently left out of "basic" STI panels (per CDC). Many infections are asymptomatic, especially in men, so people carry and transmit it without knowing. The NAAT method used here is far more sensitive than older microscopy-based tests, which is why the CDC now favors NAAT for Trichomoniasis screening in symptomatic and higher-risk individuals.

What each test detects and how it is collected

Each of the nine assays targets a different infection, uses a different method, and has its own detection window. These are general reference ranges — actual detectability in an individual case can vary, and a qualified healthcare provider should interpret results in context.

HIV (4th-generation Ag/Ab)

Blood sample

Detects: HIV-1 and HIV-2 antibodies plus the p24 antigen, which appears earlier than antibodies alone.

Typical window period: Typically detectable 18–45 days after exposure with 4th-gen testing (per CDC).

Syphilis (RPR with reflex)

Blood sample

Detects: Antibodies produced in response to Treponema pallidum infection.

Typical window period: Usually detectable 3–6 weeks after exposure; earlier tests may miss primary infection (per CDC).

Hepatitis B (HBsAg)

Blood sample

Detects: Hepatitis B surface antigen, indicating active or recent infection.

Typical window period: Typically detectable 4–10 weeks after exposure (per CDC).

Hepatitis C (HCV antibody)

Blood sample

Detects: Antibodies to the Hepatitis C virus.

Typical window period: Antibodies usually appear 8–11 weeks after exposure (per CDC).

Gonorrhea (NAAT)

Urine sample

Detects: Nucleic acid from Neisseria gonorrhoeae — the most sensitive method for urogenital infection.

Typical window period: Detectable within 1–2 weeks of exposure (per CDC).

Chlamydia (NAAT)

Urine sample

Detects: Nucleic acid from Chlamydia trachomatis.

Typical window period: Detectable within 1–2 weeks of exposure (per CDC).

HSV-1 IgG (herpes type 1)

Blood sample

Detects: Type-specific IgG antibodies to herpes simplex virus type 1 (commonly oral, can also be genital).

Typical window period: IgG antibodies typically develop 2–12 weeks after infection; some people take longer (per CDC).

HSV-2 IgG (herpes type 2)

Blood sample

Detects: Type-specific IgG antibodies to herpes simplex virus type 2 (usually genital).

Typical window period: IgG antibodies typically develop 2–12 weeks after infection; some people take longer (per CDC).

Trichomoniasis (NAAT)

Urine sample

Detects: Nucleic acid from Trichomonas vaginalis — a common but frequently underdiagnosed parasitic STI.

Typical window period: Detectable within 1–4 weeks of exposure (per CDC).

Blood tests vs. urine tests in this panel

The Comprehensive Panel uses both blood and urine samples. Six of the nine tests are run on a blood draw (HIV, Syphilis, Hepatitis B, Hepatitis C, HSV-1 IgG, HSV-2 IgG) because they look for antibodies or viral antigens circulating in the bloodstream. The other three (Gonorrhea, Chlamydia, Trichomoniasis) are run on a urine sample because those infections are diagnosed most sensitively by detecting bacterial or parasitic DNA in the urogenital tract using NAAT.

Both samples are collected in a single Labcorp Patient Service Center visit — you do not need two appointments. A standard venous blood draw plus a first-catch urine sample is all that is required.

Who should consider the Comprehensive Sexual Health Panel?

The Comprehensive Panel is worth the added cost over the Standard Panel in situations where broader coverage is meaningful. Common reasons people choose it:

  • ✓Multiple recent partners or overlapping partnerships where a wider baseline is useful.
  • ✓A new relationship and a shared decision to complete broader testing together before changing precautions.
  • ✓A previous STI diagnosis (personal or a partner's), especially involving HSV or Trichomoniasis.
  • ✓Genital or urinary symptoms without a diagnosis — broader testing can help rule infections in or out.
  • ✓Routine sexual health screening where you want the most complete picture in a single order.
  • ✓You specifically want herpes (HSV-1 / HSV-2) antibody testing, which many basic panels omit.
  • ✓You want the broadest private, self-pay panel LabTestsOnDemand offers in one checkout.

If you only want the six-infection baseline screen, the Standard Sexual Health Panel ($189) may be a better fit. If you are weighing them side by side, see the full panel STD test comparison.

What happens if a result is positive

A positive value on any screening test is a starting point, not a final diagnosis. What happens next depends on which test came back positive:

  • HIV, Syphilis, Hepatitis B: the lab runs a standard reflex confirmatory workflow automatically when the initial screen is reactive (per CDC testing guidance), and the confirmatory result appears in the same report.
  • Hepatitis C: an antibody-positive result generally requires a follow-up HCV RNA test to confirm active infection, which a healthcare provider can order.
  • Gonorrhea, Chlamydia, Trichomoniasis: a positive NAAT is generally treated as diagnostic. All three are curable with prescription treatment from a healthcare provider, and partner notification and retesting are usually recommended (per CDC).
  • HSV-1 or HSV-2 IgG: antibody results should be interpreted by a clinician, especially when values are low-positive — the CDC notes that low-positive HSV-2 IgG values sometimes require repeat testing or a different assay for clarity.

LabTestsOnDemand delivers your results to your private online account. It does not provide diagnosis, prescriptions, or treatment — a qualified healthcare provider handles the clinical next steps.

Comparing Standard vs Comprehensive?

The Standard Panel ($189) covers six infections; the Comprehensive Panel ($269) adds HSV-1, HSV-2, and Trichomoniasis. For a full side-by-side comparison of pricing, coverage, and use cases, see the full panel comparison page.

See the full panel comparison →See the Standard Panel ($189) →

How ordering works

You order online, pay one flat self-pay price of $269, and receive your Labcorp requisition and location instructions by email. You then visit any Labcorp Patient Service Center for the blood draw and urine collection, and your results are delivered to your private online account once finalized by the lab. For a step-by-step walkthrough that applies to both panels, see how confidential STD testing works or how to order an STD test online.

What the Comprehensive Panel is not

  • •Not a screen for every possible STI — HPV in particular is not included and is not part of any general blood/urine panel.
  • •Not anonymous testing — Labcorp requires a real legal name and date of birth to issue a valid lab order.
  • •Not an at-home test kit — all samples are collected in person by trained Labcorp staff.
  • •Not emergency care — for urgent symptoms, possible sexual assault, or a known high-risk exposure, contact a qualified healthcare provider or urgent care promptly.
  • •Not a substitute for individualized medical advice, diagnosis, or treatment.

Important medical note

If you have symptoms, a possible high-risk exposure, pregnancy concerns, possible sexual assault, or any other urgent medical concern, please contact a qualified healthcare provider or urgent care promptly. This page is general education and is not a substitute for individualized medical advice, diagnosis, or treatment.

Questions specific to the Comprehensive Sexual Health Panel

Why does the Comprehensive Panel cost more than the Standard Panel?

The Comprehensive Sexual Health Panel adds three tests that require additional lab methodology: HSV-1 IgG antibody testing, HSV-2 IgG antibody testing, and Trichomonas vaginalis NAAT (nucleic acid amplification testing). Each is billed separately by the lab. The $80 difference between the Standard Panel ($189) and the Comprehensive Panel ($269) reflects those three added assays.

Which infections are only included in the Comprehensive Panel?

Three tests are only in the Comprehensive Panel and are not part of the Standard Panel: HSV-1 (herpes simplex type 1) IgG antibody, HSV-2 (herpes simplex type 2) IgG antibody, and Trichomoniasis (Trichomonas vaginalis) by NAAT. Everything else — HIV, Syphilis, Hepatitis B, Hepatitis C, Gonorrhea, and Chlamydia — is in both panels.

Should I choose the Standard Panel or the Comprehensive Panel?

The Standard Panel covers the six infections the CDC lists most often for routine sexually active adult screening. The Comprehensive Panel is worth the added cost if you specifically want herpes (HSV-1 and HSV-2) antibody testing, want Trichomoniasis included, are starting a new relationship and want a wider baseline, or have had a partner with a known HSV or Trichomoniasis diagnosis. If you are unsure, a qualified healthcare provider can help you decide based on your history.

Does the Comprehensive Panel include HSV-1 and HSV-2?

Yes. The Comprehensive Panel includes both HSV-1 IgG and HSV-2 IgG antibody testing as separate assays, so the report distinguishes between the two types. Type-specific IgG testing is what the CDC recommends when herpes serology is used — non-type-specific tests can't tell HSV-1 and HSV-2 apart.

Why isn't HPV included in the Comprehensive Panel?

HPV (human papillomavirus) is not part of either LabTestsOnDemand panel. HPV screening is typically done during a cervical exam with a Pap and HPV co-test in people with a cervix, and there is no FDA-approved blood or urine HPV screening test for the general population (per CDC). For HPV screening, talk with a qualified healthcare provider — a routine well-visit or gynecology appointment is the usual path.

Can I order the Comprehensive Panel without using insurance?

Yes. The Comprehensive Panel is $269 flat self-pay. There is no insurance billing by LabTestsOnDemand — you pay once online at checkout and no claim is submitted to any insurer.

How soon after a possible exposure should I take the Comprehensive Panel?

Different infections have different window periods (see the per-test breakdown above). Gonorrhea, Chlamydia, and Trichomoniasis (NAATs) are usually detectable within 1–2 weeks. HIV by 4th-generation testing is typically detectable 18–45 days after exposure. Syphilis, Hepatitis B, Hepatitis C, and HSV IgG antibodies can take several weeks to months to appear. Testing too early can produce a false-negative. For guidance on timing after a specific exposure, see our overview of STD testing after unprotected sex, and consult a qualified healthcare provider if you have symptoms or a known high-risk exposure.

What happens if one of my results comes back positive?

A positive result on any screening test needs confirmation and clinical interpretation — a single lab value is not a diagnosis on its own. Some infections (HIV, Syphilis, Hepatitis B) have a standard reflex confirmatory workflow at the lab. For HSV antibody results in particular, low-positive values sometimes need repeat testing or a different assay for clarity (per CDC). In every case, share the result with a qualified healthcare provider who can confirm the finding, discuss treatment (if any), and advise on partner notification. LabTestsOnDemand delivers the result to your private online account; it does not provide diagnosis or treatment.

Wondering about timing after a specific exposure? See STD testing after unprotected sex. Need testing quickly? See same-day STD test options.

Sources

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Order the Comprehensive Sexual Health Panel

One flat $269 self-pay price. Nine tests — including HSV-1, HSV-2, and Trichomoniasis. Drawn at Labcorp. No insurance billing by LabTestsOnDemand. Secure results delivered to your private online account.

Order the Comprehensive Panel — $269